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Its incidence is 1 to 5 cases per million person-years, and common causative drugs are antibiotics, antimycotics, hydroxychloroquine, and diltiazem

(FDA MOTS-c listing) Emideltide / DSIP (sleep, opioid withdrawal) FDAs page notes emideltide is also referred to as delta sleeping inducing peptide (DSIP), and lists opioid withdrawal, chronic insomnia, and narcolepsy as evaluated uses

This mechanism remains less well characterized than the two previous ones and requires further independent validation